The anti-aging
cavalry is on the way.
Take care of
yourself now so you can
benefit from
coming scientific advances.
WHY
Last issue addressed how a family of enzymes called
sirtuins
hold promise for slowing aging and helping remediate
diseases such as
diabetes and Alzheimer's. Today I would like to discuss
another
research endeavor that holds promise of improving health
and slowing aging.
Human Growth Hormone prompts our bodies to grow new tissue.
HGH levels decline after puberty and continue to decline
with age. Physicians began
using Human Growth Hormones (HGH) in the 1980's to help
very short children
grow to a more normal height. That use is still common.
In 1990, Dr. Daniel Rudman gave HGH injections to elderly
nursing home residents
and got dramatic results–the residents developed bigger
muscles, thicker skin,
denser bones, more energy, lower blood pressure, fewer
wrinkles, better
vision, thicker hair, improved mood and memory and improved
sexual functioning.
Since then, thousands of athletes, actors, and celebrities
have been taking
HGH injections at about $10,000 a year. My take is that if
you are already elderly
or have certain unique health issues, it might be worth
trying. At younger ages,
however, it is risky because not enough is known about the
effects of long-term use.
Wouldn't it be nice if we could get our bodies to naturally
produce more HGH?
You can. Exercising, especially strength exercising, helps
increase your HGH levels.
On the Internet you can find hundreds of sites selling
secretagogues–over-the-counter
supplements that are supposed to prompt your body to
increase HGH production.
Do any work? There is no good way to tell. I would expect
results in a third of
users just from the placebo effects. That alone can account
for the testimonials.
Needless to say it is a buyer beware market. (I, for one,
have not purchased any.)
Researchers at the University of Washington and the VA have
been testing
capromorelin, an experimental drug from Pfizer. 395 men and
women ages 65-84
used the drug for six months. They gained an average of
three pounds in lean muscle mass
and were better able to walk a straight line (a test of
coordination, balance and strength).
A year later they showed improvement in stair climbing.
Merck reportedly is working on
a similar drug.
While the pharmaceutical companies have often had
questionable practices
in reporting research and promoting medications, I
certainly have more faith
in their products than a secretagogue found on the
Internet. The FDA does
not regard aging as a disease and sets higher approval
standards for medications
that just improve functioning as opposed to cure or manage
diseases. Thus
medications such as capromorelin will receive extra
scrutiny for the FDA.
Basic research is what I am doing when I don't know what I'm doing.
~Rocket scientist, Wernher von Braun
Finagle's First Law: If an experiment works, something has gone wrong.
Finagle's Second Law: No matter what the anticipated result, there will
always be
someone eager to (a) misinterpret it, (b) fake it, or (c) believe it happened
according
to his own pet theory.
Finagle's Third Law: In any collection of data, the figure most obviously
correct,
beyond all need of checking, is the mistake.
Finagle's Fourth Law: Once a job is fouled up, anything done to improve it only makes it worse.
Finagle's Creed: Science is true. Don't be misled by facts.
Corollaries on mistakes:
1. Nobody whom you ask for help will see it.
2. The first person who stops by, whose advice you really don't want to hear,
will see it immediately.
This article was from:
Anti-Aging
PsychologyThe following newsletter articles may be reprinted in E-zines, newsletters, newspapers, and magazines provided they the content is not edited and the attribution below is given. Formatting may be changed and you may use one of the web site pictures of the author to accompany the article.
"Dr. Michael Brickey, The Anti-Aging Psychologist, teaches people to think, feel, look and be more youthful. He is an inspiring keynote speaker and Oprah-featured author. His works include: Defy Aging, 52 Baby Steps to grow young, and Reverse Aging (anti-aging hypnosis CDs). Visit www.NotAging.com for a free report on anti-aging secrets and a free newsletter with practical anti-aging tips."